Glucosamine is an amino sugar and used in the synthesis of glycosylated proteins and lipids. Glucosamine is one of the most abundant monosaccharide in nature.
Glucosamine is present in animal bones, bone marrow and shellfish. It is also in some fungi.
Glucosamine is sold as a support for joints. Multiple studies have been done worldwide that both support and discount the benefit of this supplement. A 2009 revision of scientific studies showed inconsistent efficacy in decreasing arthritis pain and an analysis of 2010 concluded, “compared with placebo, Glucosamine chondroitin and combinations do not reduce joint pain or have an impact on narrowing of the space”. However other studies still support the use of glucosamine.
Glucosamine is not without side effects and dangers. Beyond recommended dosage, glucosamine may damage pancreatic cells increasing diabetes risk. Also more frequently glucosamine can cause stomach upset, nausea, constipation, diarrhea, headache, rash, and allergic reaction.